The Yenepoya Research Centre (YRC), established in 2008, is a constituent unit of Yenepoya (Deemed to be University). YRC is devoted to multidisciplinary research spanning fundamental, applied, and translational research. YRC has state-of-the-art facilities and resources to foster cutting-edge research and innovation involving various stakeholders. The Centre adheres to the highest ethical standards, research integrity, follows Good Laboratory Practices, and holds ISO 17025:2017 compliance certification.The biomedical research at YRC is complemented with the Yenepoya Medical College Hospital with super-speciality departments and other constituent institutions, including those specialising in alternative medicine. The passionate research team with international experience under a collaborative and inclusive environment drives the achievements by adpating transformative emerging technologies. The academic programs offered by YRC lays a robust foundation for a promising R&D career in academia and industry, as evidenced by the global alumni presence. YRC plays a pivotal role in promoting entrepreneurship among students and faculties through the Yenepoya Technology Incubator. The research thrust areas align with the nation’s effort in achieving the United Nations Sustainable Development Goals, while addressing the challenging issues at regional and national priority areas.

Vision

To generate new knowledge towards national development through quality research integrated with the highest ethical standards

Mission
  • To engage in high quality research integrating both basic and translational research across multiple disciplines, driving towards therapeutics of human health

  • To cultivate critical thinking that can spark creativity and innovation among students and young researchers to make them leaders in the field of science and technology

36

FACULTY

45

PhD Awarded

35

PATENTS

532

PUBLICATIONS

48

EXTRAMURAL GRANTS

News and Updates

MICON 2024 - Microbes for a Sustainable Future – A National Conference on 24th and 25th January 2024.

Workshop on Fundamentals and Techniques in Proteomics - Organized by CSBMM on May 29th & 31st May 2025.

Hands on Workshop on Metabolomic Analysis: Unlocking the Power of Mass Spectrometry - Organized by CSBMM on 26th & 28th May 2025.

Science Outreach Programme on 25th May 2025.

One Day Workshop on “Grant Writing for Early-Career Researchers: Breaking into Funding” - Organized by CSBMM on 23rd & 24th May 2025.

10th Annual State-level Conference of AMBKCCON 2025- Insight into Women’s Health - organized by CBMG division, in collaboration with the Biochemistry Department on 21st May 2025.

One Day Workshop on “Single Cell and Spatial Multiomics” - Organized by CSBMM on 12th March 2025.

International Women’s Day 2025 Celebration on 8th March 2025.

National Science Day celebration on 28th February 2025.

“Microglia and Neural Rhythms In Alzheimer's disease” – A Special Guest Lecture By Dr. Chinnakkaruppan Adaikkan on 20th February 2025.

The 4th National Conference MiCON 2025 on “Divergence and surveillance of microorganisms” on 25th January 2025.

Annual Day Celebration on 31st December 2024.

The snake Feeders: Ecology, Conservation and Snake Bite Solutions – A awarness session by Mr. Rithan Bopanna KG on 20 th November 2024.

Multi-omics and System Biology Approach Reveals Mitochondrial Associated Protiens In Alzheimer’s Diseases Progression – A Special Guest Lecture by Dr.Kaushik Kumar Dey on 16 th November 2024.

Mass spectrometry-based workshop on metabolomics and data analysis conducted from 26th to 28th September 2024.

Molecular Biology Techniques – A hands on training on 3rd to 6th September 2024.

Metabolomics – A workshop conducted from 3rd to 5th September 2024.

Cardiovascular Disease in India and the establishment of CSIR longitudinal cohort by Dr. Shanthanu Sengupta- A Guest Lecture on 4th September 2024.

Financial Planning: Get early, paving way to Vikasit Bharath- A guest talk by Ms. Sandhya .T. on 29th August 2024.

Basics of Data Analytics (Hybrid Mode) – A Workshop – 26th August to 6th September 2024.

Parkinson’s Disease: Our two lines to reconnoitre the Neurobiological Basis for Pathogenesis – A special Guest talk by Dr. Phalguni Anand Alladi on 24th August 2024.

Sadbhavana Diwas Celebration by NSS Unit – 20th August 2024

Aligning Grant Proposal with Sustainable Development Goals (SDG) for Viksit Bharat – A Symposium on 10th August 2024

Felicitation to Mr. Kushalappa Gowda for achieving a world record for a 25-hour yoga marathon on 2nd August 2024.

Computer - Aided Drug Design with BIOVIA Discovery Studio – Hands on Workshop – 1st to 2nd August 2024.

Understanding Office Ergonomics and Preventive Strategies in Musculosketal Disorders – A guest talk by Mr. Satyaraja. R. on 16th July 2024.

Navigating Intramural Funding Process and Application Requirements - A Workshop on 6th Jul 2024.

Biochemical and Biophysical Characterization of a Cancer drug target-Poly (ADP-ribose) polymerase 1 – A special guest lecture by Dr. Rajakumar Eerappa on 6th July 2024.

Mansoonia – Health Screening Camp and Awareness Program on 27th and June 28th 2024.

The Astrocyte Enigma: Unravelling the mystery of alpha synuclein pathology in Parkinson’s disease – A Special Guest Lecture by Dr. Aishwarya Raj on 20th June 2024.

Beating Burnout – A Guest Talk by Dr. Ravichandra Karkal on 19th June 2024

Global Warming – Awareness Program on 11th June 2024.

Enhancing Student Centred Teaching and Assessment – Short term Faculty Development Course on 27th to 29th April 2024.

Basic Biology and Clinical Application – Flow Cytometry workshop on 14th and 15th April 2024.

Drosophila Genetic Techniques – Hands on training on 28th to 30th March 2024.

National Science Day – 2024 celebration on 28th February 2024.

BUB1: A Multifaceted Kinase and its role in DNA Damage Signalling – A Special Lecture by Dr. Shyam Nyati on 19th February 2024.

Achievements

Publications

  1. Das R, Shanavas S, Das U, Kushwaha R, Chakrabarty R, Banerjee S, Chaudhury D, Shenoy P S, Bose B, Paira P. Turning the Spotlight Away from PDT: Chemodynamic Dominance of 2-(2-Bromopyridin-4-yl)-1 H-imidazo [4, 5-f][1, 10] phenanthroline Based Ru (II)/Ir (III)/Re (I) Complexes against MDA-MB-231. Journal of Medicinal Chemistry. 2025;68(24):26263-79.
  2. Rekadwad B.N.. Microbial Ecology: Microbiomes, Viromes, and Biofilms. Microbial Ecology: Microbiomes, Viromes, and Biofilms. 2024; ()
  3. Kailasam V.; Kumara B.N.; Prasad K.S.; Nirmal J.. Combination of self-assembling system and N,O-carboxymethyl chitosan improves ocular residence of anti-glaucoma drug. European Journal of Pharmaceutics and Biopharmaceutics. 2024; 197()
  4. Kumara B.N.; Shambhu R.; Shim Y.-B.; Prasad K.S.. Lysozyme activated co-delivery of latanoprost-timolol from mucoadhesive chitosan nanocomposite to manage glaucoma. RSC Pharmaceutics. 2024; 1(3)
  5. Rekadwad B.N.. Taxonomic Approaches for Uncultivated Prokaryotes. Modern Taxonomy of Bacteria and Archaea: New Methods, Technology and Advances. 2024; ()
  6. Palollathil A.; Babu S.; Abhinand C.S.; Mathew R.T.; Vijayakumar M.; Prasad T.S.K.. Proteomic profiling of oral squamous cell carcinoma tissues reveals altered immune-related proteins: implications for personalized therapy. Expert Review of Proteomics. 2024; 21(11)
  7. Maske V.B.; Sarode S.C.; Rekadwad B.N.. Sequence-Based Analysis of Tyrosinase-Producing Bacteria for Rapid Identification, Differentiation, and Comparison. Acta Microbiologica Bulgarica. 2024; 40(3)
  8. Hemavathi K.N.; Skariyachan S.; Raju R.; Keshava Prasad T.S.; Abhinand C.S.. Computational screening of potential anti-inflammatory leads from Jeevaneeya Rasayana plants targeting COX-2 and 5- LOX by molecular docking and dynamic simulation approaches. Computers in Biology and Medicine. 2024; 171()
  9. Thimmappa P.Y.; Nair A.S.; D'silva S.; Aravind A.; Mallya S.; Soman S.P.; Guruprasad K.P.; Shastry S.; Raju R.; Prasad T.S.K.; Joshi M.B.. Neutrophils display distinct post-translational modifications in response to varied pathological stimuli. International Immunopharmacology. 2024; 132()
  10. Sapna K.; Shim Y.-B.; Arun A.B.; Prasad K.S.. Diagnosis of Neglected Tropical Zoonotic Disease, Leptospirosis in a Clinical Sample Using a Photothermal Immunosensor. Analytical Chemistry. 2024; 96(1)
  11. Singh I.; Hoti S.L.; Chauhan N.; Joshi R.K.; Prasad T.S.K.; Sarikhani M.; Kaushik M.; Unger B.S.; Jadhav P.; Modi P.K.. Immunomodulation of streptozotocin induced Type 1 diabetes mellitus in mouse model by Macrophage migration inhibitory factor-2 (MIF-2) homologue of human lymphatic filarial parasite, Wuchereria bancrofti. Acta Tropica. 2024; 252()
  12. DH H.S.; Sultana R.; Prabhu A.; S.R P.; Mohanto S.; Subramaniyan V.. Biomedicine and pharmacotherapeutic effectiveness of combinatorial atorvastatin and quercetin on diabetic nephropathy: An in vitro study. Biomedicine and Pharmacotherapy. 2024; 174()
  13. Mitra A.; Mandal S.; Bose B.; Shenoy P S.. Unlocking the Potential of Obestatin: A Novel Peptide Intervention for Skeletal Muscle Regeneration and Prevention of Atrophy. Molecular Biotechnology. 2024; 66(5)
  14. Spandana K.J.; Bhagya N.. Serine protease: Structure, classification, mechanism and role in breast cancer. Pathophysiological Aspects of Proteases in Cancer. 2024; ()
  15. Murugan S.S.; Seong G.H.; Jayachandran V.. Carboxymethyl Chitosan Derivatives in Biosensing Applications. Advances in Polymer Science. 2024; 292()
  16. Rekadwad B.N.; Maske V.B.. A Protocol for Screening, Cultivation, and Molecular Identification of Rare and Slow-Growing Actinomycetes with Biosynthetic Gene Clusters. Protocols of Actinomycetes: Microbiology to Gene Editing. 2024; ()
  17. Krishnan D.; Babu S.; Raju R.; Veettil M.V.; Prasad T.S.K.; Abhinand C.S.. Epstein–Barr Virus: Human Interactome Reveals New Molecular Insights into Viral Pathogenesis for Potential Therapeutics and Antiviral Drug Discovery. OMICS A Journal of Integrative Biology. 2024; 28(1)
  18. Manivasagan P.; Venkatesan J.; Jang E.-S.. Nanophototherapy: Preparations and Applications. Nanophototherapy: Preparations and Applications. 2024; ()
  19. Bushra K.A.; Shim Y.-B.; Prasad K.S.. Two-Dimensional Ternary Nanocomposite-Decorated Cellulose Field Effect Transistor for Nonenzymatic Sweat Glucose Sensing. ACS Applied Nano Materials. 2024; 7(1)
  20. Prabhu A.. Applications of Spices in Nutraceuticals. Herbal Nutraceuticals: Products and Processes. 2024; ()
  21. Hussain M.S.; Maqbool M.; Shaikh N.K.; Agrawal M.; Sultana A.. Therapeutic Landscape of Diabetic Nephropathy: Insights from Long Noncoding RNAs. Clinical Diabetology. 2024; 13(5)
  22. Priyanka P.; Gopalakrishnan A.P.; Nisar M.; Shivamurthy P.B.; George M.; John L.; Sanjeev D.; Yandigeri T.; Thomas S.D.; Rafi A.; Dagamajalu S.; Velikkakath A.K.G.; Abhinand C.S.; Kanekar S.; Prasad T.S.K.; Balaya R.D.A.; Raju R.. A global phosphosite-correlated network map of Thousand And One Kinase 1 (TAOK1). International Journal of Biochemistry and Cell Biology. 2024; 170()
  23. Mathew S.; Vijaya Kumar K.; Prabhu A.; Shastry R.P.; Rajesh K.S.. Braided silk sutures coated with photoreduced silver nanoparticles for eradicating Staphylococcus aureus and Streptococcus mutans infections. Journal of Microbiological Methods. 2024; 220()
  24. Rekadwad B.N.. Microbe Hunting: Unveiling the Secrets of Microorganisms through Assessment, Sequencing, and Bioinformatics Analysis. Microbe Hunting: Unveiling the Secrets of Microorganisms through Assessment, Sequencing, and Bioinformatics Analysis. 2024; ()
  25. Mahin A.; Soman S.P.; Modi P.K.; Raju R.; Keshava Prasad T.S.; Abhinand C.S.. Meta-analysis of the serum/plasma proteome identifies significant associations between COVID-19 with Alzheimer’s/Parkinson’s diseases. Journal of NeuroVirology. 2024; 30(1)
  26. Prasad K.S.; Naveen M.H.; Manisha H.; Suriani A.B.; Babu T.G.S.; Shim Y.-B.. Dual heteroatoms doped nanocarbons: electrocatalysts for hydrogen peroxide synthesis. Carbon Letters. 2024; 34(4)
  27. Rekadwad B.N.; Sudhakar K.P.. antiSMASH Genome Mining and Genome-Wide Analysis of Gene Clusters in Actinopolyspora Species. Protocols of Actinomycetes: Microbiology to Gene Editing. 2024; ()
  28. Fernandes N.B.; Velagacherla V.; Spandana K.J.; N B.; Mehta C.H.; Gadag S.; Sabhahit J.N.; Nayak U.Y.. Co-delivery of lapatinib and 5-fluorouracil transfersomes using transpapillary iontophoresis for breast cancer therapy. International Journal of Pharmaceutics. 2024; 650()
  29. Rekadwad B.N.; Gonzalez J.M.; Li W.-J.. Editorial: Last universal common ancestor and origin of life: what uncultivated Bacteria, Archaea, and extremophiles can tell us. Frontiers in Microbiology. 2024; 15()
  30. Rekadwad B.N.. The reverse zoonosis transfer cycle from the human-animal-plant-environment interface: How antibiotic-resistant bacteria from humans threaten the environment and fuel the rise of superbugs. Medical Hypotheses. 2024; 186()
  31. Suresh Poojary P.; Shreya A.B.; Mutalik S.; Sachdev D.; Taneja N.K.; Raghu S.V.; Pasricha R.; Ananda H.; Pramoda K.; Vani Lakshmi R.; Adiga S.K.; Kalthur G.. Mitigating effect of chitosan-coated zinc oxide nanoparticles on cryopreservation-induced DNA damage in human spermatozoa. Journal of Taibah University for Science. 2024; 18(1)
  32. Kumara B.N.; Naveen M.H.; Sonia J.; Rafi M.; Bang J.H.; Prasad K.S.. A simple naked eye detection of Pb2+ on a gold nanocluster decorated disposable paper spot arrays. Physica Scripta. 2024; 99(5)
  33. Shaikh S.B.; Prabhu A.; Akarsha B.; Rahamathulla M.P.; Sha M.; Bhandary Y.P.. Lung as a target for COVID-19: Mechanistic insights and probable candidate molecules for cure. Journal of Infection and Public Health. 2024; 17(4)
  34. Venkatesan J.; Anil S.. Nanomaterials for Osteogenic Differentiation of Mesenchymal Stem Cells for Bone Tissue Engineering. Comprehensive Hematology and Stem Cell Research: Volume 1-5. 2024; 4()
  35. Palatty P.L.; Sacheendran D.; Raghu S.V.; Arora R.; Rao S.; Baliga M.S.. Dietary agents in the prevention of radiation-induced nausea and vomiting (RINV): review addressing the scientific observations, benefits, lacunae and future direction. International Journal of Radiation Biology. 2024; 100(8)
  36. Moideen F.M.; Bhandary Y.P.. The Inefficiency of Low-concentration Curcumin Intervention in Ameliorating Chronic-stage Pulmonary Fibrosis. Current Bioactive Compounds. 2024; 20(2)
  37. Rekadwad B.N.; Lian Z.-H.; Jiao J.-Y.; Li W.-J.. Phylogenetics and Phylogenomics for Inferring Relationships of Bacteria and Archaea Phyla. Modern Taxonomy of Bacteria and Archaea: New Methods, Technology and Advances. 2024; ()
  38. Vishrutha K.S.; Ulla H.; Raveendra Kiran M.; Bhat B.R.; Adhikari A.V.. Utilization of newly configured carbazole-cyanopyridone structural hybrids towards achieving high-performance cyan fluorescent organic light-emitting diodes. Materials Advances. 2024; 5(6)
  39. Kotimoole C.N.; Ramya V.K.; Kaur P.; Reiling N.; Shandil R.K.; Narayanan S.; Flo T.H.; Prasad T.S.K.. Discovery of Species-Specific Proteotypic Peptides To Establish a Spectral Library Platform for Identification of Nontuberculosis Mycobacteria from Mass Spectrometry-Based Proteomics. Journal of Proteome Research. 2024; 23(3)
  40. Manivasagan P.; Venkatesan J.; Jang E.-S.. Preface. Nanophototherapy: Preparations and Applications. 2024; ()
  41. Hemavathi K.N.; Middha S.K.; Raju R.; Pilankatta R.; Keshava Prasad T.S.; Abhinand C.S.. Computational screening of phytocompounds from C. amboinicus identifies potential inhibitors of influenza A (H3N2) virus by targeting hemagglutinin. Journal of Biomolecular Structure and Dynamics. 2024; ()
  42. Harsha K.; Divya Lakshmanan M.. Proteases in DNA damage, repair, and radioresistance: Cellular and molecular aspects. Pathophysiological Aspects of Proteases in Cancer. 2024; ()
  43. Manivasagan P.; Joe A.; Han H.-W.; Seo S.-H.; Venkatesan J.; Jang E.-S.. Introduction to nanophototherapy. Nanophototherapy: Preparations and Applications. 2024; ()
  44. Sequeira J.J.; Vinuthalakshmi K.; Das R.; van Driem G.; Mustak M.S.. Corrigendum: The maternal U1 haplogroup in the Koraga tribe as a correlate of their North Dravidian linguistic affinity (Frontiers in Genetics, (2024), 14, (1303628), 10.3389/fgene.2023.1303628). Frontiers in Genetics. 2024; 15()
  45. Shaheer K.; Prabhu B.S.; Ali H.S.; Lakshmanan-M D.. Breast cancer cells are sensitized by piperine to radiotherapy through estrogen receptor-? mediated modulation of a key NHEJ repair protein- DNA-PK. Phytomedicine. 2024; 122()
  46. Miliotis G.; Sengupta P.; Hameed A.; Chuvochina M.; McDonagh F.; Simpson A.C.; Parker C.W.; Singh N.K.; Rekha P.D.; Morris D.; Raman K.; Kyrpides N.C.; Hugenholtz P.; Venkateswaran K.. Novel spore-forming species exhibiting intrinsic resistance to third- and fourth-generation cephalosporins and description of Tigheibacillus jepli gen. nov., sp. nov.. mBio. 2024; 15(4)
  47. Yashaswini Devi G.V.; Dalavi P.A.; Seong G.H.; Venkatesan J.. Nanomaterials in marine science. Handbook of Nanomaterials, Volume 2: Biomedicine, Environment, Food, and Agriculture. 2024; ()
  48. Rani J.M.S.; Akkarshana P.; Neelaveni V.; Mohan S.; Rekha P.D.; Rao R.M.; Muthulakshmi L.. Evaluation of the inhibitory potential of bioactive compounds against SARS-CoV-2 by in silico approach. Journal of Molecular Modeling. 2024; 30(3)
  49. Bajire S.K.; Shastry R.P.. Synergistic effects of COVID-19 and Pseudomonas aeruginosa in chronic obstructive pulmonary disease: a polymicrobial perspective. Molecular and Cellular Biochemistry. 2024; 479(3)
  50. Sonia J.; Viju N.C.; Dsouza R.; Venkadesh A.; Naveen M.H.; Prasad K.S.. Surface engineered low-cost paper electrodes for enhanced electrocatalytic activity. Electrochimica Acta. 2024; 474()

Testimonials

An excellent facility with superior scope

Dr. VijayRaghavan

Secretary, DBT, New Delhi
Nice to see a bubbling group of researchers in a new upcoming research centre

Bharat Ratna Dr. C. N. R Rao

Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore
Proud to see such wonderful work at the facility and in faraway Mangalore

Dr. A. K. D’Cruz

Director-Tata Memorial Hospital, Mumbai
I was excited to see the advancement done by the institution in every aspect of medical science including latest laboratory in the premise. I pray the God that this institution will prosper and give benefit to the nation in health sector

Shri Shripad Yesso Naik

The Union Minister of AYUSH, Government of India
Wonderful facility! Research is the future to solve issues in medicine. I am very impressed with the passion of the faculty in R & D. Keep up the good work

Faizal E. Kottikollon and Shabana Faizal

Faizal Shabana Foundation, Bangalore
It is very good to see how committed you are with research

Dr. Claudio Almeida Quadros

Bahia State University, Brazil
An ideal facility positioning with cutting edge research and talented researchers right in the middle of a hospital, just what is needed for the translational research

Prof. Pauline Ford

School of Dentistry, The University of Queensland, Australia

Certifications