The Yenepoya Research Centre (YRC), established in 2008, is a constituent unit of Yenepoya (Deemed to be University). YRC is devoted to multidisciplinary research spanning fundamental, applied, and translational research. YRC has state-of-the-art facilities and resources to foster cutting-edge research and innovation involving various stakeholders. The Centre adheres to the highest ethical standards, research integrity, follows Good Laboratory Practices, and holds ISO 17025:2017 compliance certification.The biomedical research at YRC is complemented with the Yenepoya Medical College Hospital with super-speciality departments and other constituent institutions, including those specialising in alternative medicine. The passionate research team with international experience under a collaborative and inclusive environment drives the achievements by adpating transformative emerging technologies. The academic programs offered by YRC lays a robust foundation for a promising R&D career in academia and industry, as evidenced by the global alumni presence. YRC plays a pivotal role in promoting entrepreneurship among students and faculties through the Yenepoya Technology Incubator. The research thrust areas align with the nation’s effort in achieving the United Nations Sustainable Development Goals, while addressing the challenging issues at regional and national priority areas.

Vision

To generate new knowledge towards national development through quality research integrated with the highest ethical standards

Mission
  • To engage in high quality research integrating both basic and translational research across multiple disciplines, driving towards therapeutics of human health

  • To cultivate critical thinking that can spark creativity and innovation among students and young researchers to make them leaders in the field of science and technology

32

FACULTY

45

PhD Awarded

35

PATENTS

532

PUBLICATIONS

48

EXTRAMURAL GRANTS

News and Updates

MICON 2024 - Microbes for a Sustainable Future – A National Conference on 24th and 25th January 2024.

Workshop on Fundamentals and Techniques in Proteomics - Organized by CSBMM on May 29th & 31st May 2025.

Hands on Workshop on Metabolomic Analysis: Unlocking the Power of Mass Spectrometry - Organized by CSBMM on 26th & 28th May 2025.

Science Outreach Programme on 25th May 2025.

One Day Workshop on “Grant Writing for Early-Career Researchers: Breaking into Funding” - Organized by CSBMM on 23rd & 24th May 2025.

10th Annual State-level Conference of AMBKCCON 2025- Insight into Women’s Health - organized by CBMG division, in collaboration with the Biochemistry Department on 21st May 2025.

One Day Workshop on “Single Cell and Spatial Multiomics” - Organized by CSBMM on 12th March 2025.

International Women’s Day 2025 Celebration on 8th March 2025.

National Science Day celebration on 28th February 2025.

“Microglia and Neural Rhythms In Alzheimer's disease” – A Special Guest Lecture By Dr. Chinnakkaruppan Adaikkan on 20th February 2025.

The 4th National Conference MiCON 2025 on “Divergence and surveillance of microorganisms” on 25th January 2025.

Annual Day Celebration on 31st December 2024.

The snake Feeders: Ecology, Conservation and Snake Bite Solutions – A awarness session by Mr. Rithan Bopanna KG on 20 th November 2024.

Multi-omics and System Biology Approach Reveals Mitochondrial Associated Protiens In Alzheimer’s Diseases Progression – A Special Guest Lecture by Dr.Kaushik Kumar Dey on 16 th November 2024.

Mass spectrometry-based workshop on metabolomics and data analysis conducted from 26th to 28th September 2024.

Molecular Biology Techniques – A hands on training on 3rd to 6th September 2024.

Metabolomics – A workshop conducted from 3rd to 5th September 2024.

Cardiovascular Disease in India and the establishment of CSIR longitudinal cohort by Dr. Shanthanu Sengupta- A Guest Lecture on 4th September 2024.

Financial Planning: Get early, paving way to Vikasit Bharath- A guest talk by Ms. Sandhya .T. on 29th August 2024.

Basics of Data Analytics (Hybrid Mode) – A Workshop – 26th August to 6th September 2024.

Parkinson’s Disease: Our two lines to reconnoitre the Neurobiological Basis for Pathogenesis – A special Guest talk by Dr. Phalguni Anand Alladi on 24th August 2024.

Sadbhavana Diwas Celebration by NSS Unit – 20th August 2024

Aligning Grant Proposal with Sustainable Development Goals (SDG) for Viksit Bharat – A Symposium on 10th August 2024

Felicitation to Mr. Kushalappa Gowda for achieving a world record for a 25-hour yoga marathon on 2nd August 2024.

Computer - Aided Drug Design with BIOVIA Discovery Studio – Hands on Workshop – 1st to 2nd August 2024.

Understanding Office Ergonomics and Preventive Strategies in Musculosketal Disorders – A guest talk by Mr. Satyaraja. R. on 16th July 2024.

Navigating Intramural Funding Process and Application Requirements - A Workshop on 6th Jul 2024.

Biochemical and Biophysical Characterization of a Cancer drug target-Poly (ADP-ribose) polymerase 1 – A special guest lecture by Dr. Rajakumar Eerappa on 6th July 2024.

Mansoonia – Health Screening Camp and Awareness Program on 27th and June 28th 2024.

The Astrocyte Enigma: Unravelling the mystery of alpha synuclein pathology in Parkinson’s disease – A Special Guest Lecture by Dr. Aishwarya Raj on 20th June 2024.

Beating Burnout – A Guest Talk by Dr. Ravichandra Karkal on 19th June 2024

Global Warming – Awareness Program on 11th June 2024.

Enhancing Student Centred Teaching and Assessment – Short term Faculty Development Course on 27th to 29th April 2024.

Basic Biology and Clinical Application – Flow Cytometry workshop on 14th and 15th April 2024.

Drosophila Genetic Techniques – Hands on training on 28th to 30th March 2024.

National Science Day – 2024 celebration on 28th February 2024.

BUB1: A Multifaceted Kinase and its role in DNA Damage Signalling – A Special Lecture by Dr. Shyam Nyati on 19th February 2024.

Achievements

Publications

  1. Krishnan S.; Kanthaje S.; Rekha P.D.; Mujeeburahiman M.; Ratnacaram C.K.. Expanding frontiers in liquid biopsy-discovery and validation of circulating biomarkers in renal cell carcinoma and bladder cancer. International Review of Cell and Molecular Biology. 2025; 391()
  2. Rai A.B.; Codi J.A.K.; Kotimoole C.N.; Ramesh P.; Narayana V.K.; Shaji V.; Prasad T.S.K.. Data-Independent Acquisition Analysis to Identify Serum Biomarkers and Neoantigens for Differentiating Colorectal Cancer from Inflammatory Bowel Diseases. Journal of Proteome Research. 2025; ()
  3. Hameed A.; McDonagh F.; Sengupta P.; Miliotis G.; Sivabalan S.K.M.; Szydlowski L.; Simpson A.; Singh N.K.; Rekha P.D.; Raman K.; Venkateswaran K.. Neobacillus driksii sp. nov. isolated from a Mars 2020 spacecraft assembly facility and genomic potential for lasso peptide production in Neobacillus. Microbiology Spectrum . 2025; 13(1)
  4. Nekrakalaya B.; Kotimoole C.N.; Arefian M.; Prasad T.S.K.; Palliyath G.K.; Veerappa Hanumanthappa P.; Pandian Ramasubramania T.P.; Bangalore Jayaseelan N.K.; Muddumadiah C.; Santhappan P.; Muliyar Krishna R.. A Gel-Free Genome Annotation Provides Insights into the Proteome of the Oomycete Phytophthora meadii, a Disease-Causing Pathogen in Economically Important Crops. OMICS A Journal of Integrative Biology. 2025; ()
  5. Pavan S.R.; Prabhu A.. Black Phosphorus for Biosensing and Imaging Applications. Two-Dimensional Nanomaterials for Biosensing and Imaging Applications. 2025; ()
  6. Salam A.S.A.; Anchan R.V.; Murugan S.S.; Majhi D.; Venkatesan J.. The Potential Use of Algae-Derived Green Nanomaterials in Cancer Therapy. Nano-formulation of Dietary Phytochemicals for Cancer Management. 2025; ()
  7. Manzoor M.; Suryavanshi M.V.; Mujeeburahiman M.; Arun A.B.; Miller A.W.; Shouche Y.S.; Rekha P.D.. Urine microbiome profiles in patients with different types of kidney stones. FEMS Microbiology Letters. 2025; 372()
  8. Prashanth S.; Kadandelu M.; Raghu S.V.; Prasad K.S.; Adhikari A.V.. Conductive nano nickel oxide/hydroxide paper electrochemical sensor for serotonin detection in genetically engineered Drosophila. Journal of Materials Chemistry B. 2025; ()
  9. Dcunha R.; Aravind A.; Bhaskar S.; Mutalik S.; Mutalik S.; Kalthur S.G.; Kumar A.; Hegde P.; Adiga S.K.; Zhao Y.; Kannan N.; Prasad T.S.K.; Kalthur G.. Enhanced cell survival in prepubertal testicular tissue cryopreserved with membrane lipids and antioxidants rich cryopreservation medium. Cell and Tissue Research. 2025; 399(1)
  10. Kapoor A.; Meitei N.S.; Bisht V.S.; Najar M.A.; Giri K.; Prasad T.S.K.; Ambatipudi K.. Lactation stage-specific variations in health and lipid-associated milk fat globule membrane proteins in Holstein Friesian cow and Murrah buffalo. International Dairy Journal. 2025; 160()
  11. Bhat S.; Narayana V.K.; Prasad T.S.K.. Metabolomics studies in cushing’s syndrome: recent developments and perspectives. Expert Review of Proteomics. 2025; 22(2)
  12. Ramesh P.; Kandel Codi J.A.; Prasad T.S.K.. Proteins Biomarkers for Diagnosing Gastric Cancers: Perspectives Through Mass Spectrometry-Based Discoveries. Protein Biomarkers: Discovery and Applications in Clinical Diagnostics. 2025; ()
  13. Yukta; Sarkar O.; Mutthuraj D.; Dagamajalu S.; Basalingappa K.M.. Small Molecule Therapeutics in Breast Cancer: Current Approaches and Future Directions. Small Molecules for Cancer Treatment. 2025; ()
  14. Parate S.S.; Viayakumar M.; Prasad T.S.K.. Ex Vivo Drug Assay as a Potential Hospital-Based Testing Platform for Clinical Research and Personalized Treatment for Solid Tumors. Protein Biomarkers: Discovery and Applications in Clinical Diagnostics. 2025; ()
  15. Upadhyay S.; Shetty R.; Prasad T.S.K.. Prospects for the Discovery of Actionable Molecular Targets for Triple Negative Breast Cancer. Protein Biomarkers: Discovery and Applications in Clinical Diagnostics. 2025; ()
  16. Aravind A.; Shaji V.; Ahmed M.; Dagamajalu S.; Vijayakumar M.; Prasad T.S.K.; Raju R.. An assembled molecular signaling map of interleukin-24: a resource to decipher its multifunctional immunoregulatory role in pathophysiological conditions. Frontiers in Immunology. 2025; 16()
  17. Gopalakrishnan A.P.; Shivamurthy P.B.; Ahmed M.; Ummar S.; Ramesh P.; Thomas S.D.; Mahin A.; Nisar M.; Soman S.; Subbannayya Y.; Raju R.. Positional distribution and conservation of major phosphorylated sites in the human kinome. Frontiers in Molecular Biosciences. 2025; 12()
  18. Sreelakshmi K.; Hemavathi K.N.; Raju R.; Sameer K.V.B.; Keshava Prasad T.S.; Sudhakaran P.R.; Abhinand C.S.. Identification and stability analysis of potential ADP-ribose modification sites on vascular endothelial growth factor (VEGF) through molecular dynamics simulation. Journal of Biomolecular Structure and Dynamics. 2025; 43(7)
  19. Suchitha G.P.; Upadhyay S.S.; Pervaje R.; Keshava Prasad T.S.; Dagamajalu S.. Uncovering the anticancer effects of Bhallataka Taila in lung cancer: A metabolomic and network pharmacology approach. BioImpacts. 2025; 15()
  20. Rahmath N.A.K.; Lin S.-Y.; Young C.-C.; Hameed A.. Volatile dimethyl disulphide emission from Burkholderia cepacia LS-044 suppresses metabolism and budding in caspofungin-resistant Nakaseomyces glabratus NT2. Scientific Reports. 2025; 15(1)
  21. Suchitha G.P.; Rai A.B.; Pervaje R.; Kotimoole C.N.; Modi P.K.; Keshava Prasad T.S.; Dagamajalu S.. Proteomic analysis reveals anticancer mechanisms of Bhallataka taila in inhibiting lung cancer progression and metastasis. Molecular Omics. 2025; 21(2)
  22. Avvadukkam J.; Kodoth A.K.; Subramani T.M.; Bhandari S.G.; Kaiprath D.; Kunhanna S.B.; Venugopal D.M.; Raghu S.V.. Development of pH-Responsive Hydrogel Excipient From Karaya Gum for Improved Oral Delivery of Donepezil Hydrochloride in Alzheimer's Disease Treatment. Journal of Applied Polymer Science. 2025; 142(12)
  23. Sunitha M.S.; Naik P.; Vishnumurthy K.A.; Adhikari A.V.. Synthesis of nonlinear heteroaromatic donor–acceptor conjugated polymers: Structural, theoretical, electrochemical, and optical properties. Polymer Engineering and Science. 2025; 65(4)
  24. V S S.; De S.; Shetty S.; K D.; A R Y.; A J.; Prabhu S.; Pinto R.. Mechanistic insights into the formation of phase pure V2O5 2D nanostructures: Advanced fourier transform-raman spectroscopy analysis. Thin Solid Films. 2025; 815()
  25. Ahmed S.M.; Laha S.; Ifthikar M.A.; Das R.; Das S.P.. MCM10: A potential biomarker for cervical cancer and precancerous lesions. Gene. 2025; 936()
  26. Shastry R.P.; Hameed A.; Banerjee S.; Prabhu A.; Bajire S.K.; Pavan S.R.; Dhanyashree H.R.; Kotimoole C.N.; Stothard P.; Surya S.; Keshava Prasad T.S.; Shetty R.; Shen F.-T.; Bhandary Y.P.. Tryptic oncopeptide secreted from the gut bacterium Cronobacter malonaticus PO3 promotes colorectal cancer. Scientific Reports. 2025; 15(1)
  27. Shah S.; Paudel M.R.; Thapa B.B.; Sharma H.; Kashyap A.K.; Rekadwad B.N.; Sharma R.; Sharma J.; Pant B.. Extract from endophytic Fusarium isolates stimulates seed germination of the host and protocorm development of non-host orchids. Communicative and Integrative Biology . 2025; 18(1)
  28. Sasikumar J.; Shaikh H.A.; Naik B.; Laha S.; Das S.P.. Emergence of fungal hybrids – Potential threat to humans. Microbial Pathogenesis. 2025; 200()
  29. Biju P.; Shenoy M.M.; Tellis R.; Bhat R.; Das R.; Prabhu A.; Ahmed M.G.; Ghate V.. Novel Ketoconazole-Loaded Niosomal Gel with Carbamide for Enhanced Topical Delivery and Skin Hydration in Fungal Infections. Journal of Pharmaceutical Innovation. 2025; 20(2)
  30. Das U.; Shanavas S.; Jayaprakash M.; Senthil Kumar A.; Kushwaha R.; Mondal D.; Maity S.; Ghosh P.; Kar B.; Banerjee S.; Sudheer Shenoy P.; Bose B.; Paira P.. Reactive Oxygen Species Inducing Triazolylpyridine-Based Ru(II)/Ir(III) Complexes for Therapeutically Enhanced Triple-Negative Breast Cancer Treatment. Journal of Medicinal Chemistry. 2025; 68(3)
  31. Mallick S.; Narayana V.K.; Rai A.B.; Upadhyay S.S.; Prasad T.S.K.; P S.S.; Bose B.. Hematopoietic stem cell conditioned media induces apoptosis in colorectal cancer stem cells via dysregulation of HSP90 and 26S proteasome system. International Journal of Biochemistry and Cell Biology. 2025; 184()
  32. Farooq J.; Sultana R.; Prabhu A.; Kayarohanam S.; Gupta G.; Subramaniyan V.. Mitigation of 5-Fluorouracil-Induced Nephrotoxicity: The Protective Role of Thymoquinone and Hesperidin in vitro and in vivo. Natural Resources for Human Health. 2025; 5(2)
  33. M D.L.. Stress mediators: Cancer's double Dilemma – Navigating the error-prone path of non-homologous end joining. Medical Hypotheses. 2025; 200()
  34. Singh S.R.; Kittur B.; Bhavi S.M.; Thokchom B.; Padti A.C.; Bhat S.S.; Bajire S.K.; Shastry R.P.; Srinath B.S.; Sillanpää M.; Harini B.P.; Yarajarla R.B.. The effect of Clitoria ternatea L. flowers-derived silver nanoparticles on A549 and L-132 human cell lines and their antibacterial efficacy in Caenorhabditis elegans in vivo. Hybrid Advances. 2025; 8()
  35. Nisar M.; Soman S.P.; Sreelan S.; John L.; Pinto S.M.; Kandasamy R.K.; Subbannayya Y.; Prasad T.S.K.; Kanekar S.; Raju R.; Devasahayam Arokia Balaya R.. ProteoArk: A One-Pot Proteomics Data Analysis and Visualization Tool for Biologists. Journal of Proteome Research. 2025; 24(3)
  36. Kumara B.N.; Aziz R.A.; Sathish Kumar M.; Raghu S.V.; Sudhakara Prasad K.. Understanding photoluminescent carbon nanodots interaction with Human Corneal Epithelial cells and Drosophila melanogaster model. Biochemical and Biophysical Research Communications. 2025; 771()
  37. Rawat A.; Antil N.; Meenakshi; Deshmukh B.; Rai A.B.; Nagar A.; Kumar N.; Prasad T.S.K.; Karmodiya K.; Sharma P.. PfPPM2 signalling regulates asexual division and sexual conversion of human malaria parasite Plasmodium falciparum. Nature Communications . 2025; 16(1)
  38. Bisht V.S.; Kumar D.; Najar M.A.; Giri K.; Kaur J.; Prasad T.S.K.; Ambatipudi K.. Drug response-based precision therapeutic selection for tamoxifen-resistant triple-positive breast cancer. Journal of Proteomics. 2025; 310()
  39. Moharana S.S.; Mallick S.; Pinto J.R.; Shenoy P S.; Bose B.. Osteo-inductive potential of homoeopathy potencies of Asafoetida on multipotent mesenchymal stem cells in vitro. 3 Biotech. 2025; 15(5)
  40. Naik B.; Sasikumar J.; Das S.P.. From Skin and Gut to the Brain: The Infectious Journey of the Human Commensal Fungus Malassezia and Its Neurological Consequences. Molecular Neurobiology. 2025; 62(1)
  41. Krishna S.; Sequeira J.J.; Mustak M.S.; Das R.. Mitochondrial DNA HVRII (Poly-C) and HVRIII (Poly-CA) tandem repeat variation in the Koraga population. Egyptian Journal of Medical Human Genetics. 2025; 26(1)
  42. Mandal S.; Mitra A.; Bose B.; Shenoy P S.. Quercetin and Kaempferol Mitigate Endotoxin-Induced Skeletal Muscle Wasting by Inhibiting KLF15 Expression and Restoring the Antioxidant System. FASEB Journal. 2025; 39(13)
  43. Ghosh D.; Aravind N.A.. Reptile Love: Are We Treating Them Humanely?. Animal Behavior in the Tropics: Vertebrates. 2025; ()
  44. Thomas M.R.; Badekila A.K.; Pai V.; Nijil S.; Bhandary Y.; Rai A.; Kini S.. Navigating Tumor Microenvironment Barriers with Nanotherapeutic Strategies for Targeting Metastasis. Advanced Healthcare Materials. 2025; 14(7)
  45. Sanjana N.S.; Maske V.B.; Devasya R.P.; Rekadwad B.N.. Draft genome sequence of an antibiotic-resistant Heyndrickxia oleronia strain UL23-01-03 isolated from the Arabian Sea coast, Dakshina Kannada, India. Microbiology Resource Announcements. 2025; 14(7)
  46. Roy O.; Ammankallu S.; Narayana V.K.; Narayana C.; Hebbar S.; Adiga P.K.; Joshi M.B.; Gowda J.; Kumar A.; Adiga S.K.; Ritting M.; Kannan N.; Prasad T.S.K.; Kalthur G.. Mass Spectrometric Analysis of Clomiphene Citrate-induced Changes in the Secretome Profile of PAX8-positive Human Fallopian Tube Secretory Epithelial Cells and Identification of Biomarkers Relevant to Reproduction and Pregnancy. Reproductive Sciences. 2025; 32(7)
  47. Narayanan V A.; Yamajala R.B.R.D.; Venkatesan J.; Pang M.-G.; Gedda G.. Emerging Carbon Dots Nanomaterials for Ovarian Cancer Diagnosis and Therapy. Current Drug Targets. 2025; ()
  48. Rai A.; Subramaniyan Y.; Fathima F.; Rekha P.D.. Broad-spectrum antimicrobial properties of linalool: supporting its pharmacological use in chronic wound infections by pathogens within the ESKAPE group and polymicrobial biofilms. World Journal of Microbiology and Biotechnology. 2025; 41(3)
  49. Pinto J.R.; Bhat K.D.; Bose B.; Shenoy P.S.. Correction to: Irisin: muscle’s novel player in endoplasmic reticulum stress and disease (Molecular and Cellular Biochemistry, (2025), 10.1007/s11010-025-05225-y). Molecular and Cellular Biochemistry. 2025; ()
  50. Suchithra K.V.; Hameed A.; Surya S.; Mahammad S.; Arun A.B.. Dual phage-incorporated electrospun polyvinyl alcohol-eudragit nanofiber matrix for rapid healing of diabetic wound infected by Pseudomonas aeruginosa and Staphylococcus aureus. Drug Delivery and Translational Research. 2025; 15(3)

Testimonials

An excellent facility with superior scope

Dr. VijayRaghavan

Secretary, DBT, New Delhi
Nice to see a bubbling group of researchers in a new upcoming research centre

Bharat Ratna Dr. C. N. R Rao

Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore
Proud to see such wonderful work at the facility and in faraway Mangalore

Dr. A. K. D’Cruz

Director-Tata Memorial Hospital, Mumbai
I was excited to see the advancement done by the institution in every aspect of medical science including latest laboratory in the premise. I pray the God that this institution will prosper and give benefit to the nation in health sector

Shri Shripad Yesso Naik

The Union Minister of AYUSH, Government of India
Wonderful facility! Research is the future to solve issues in medicine. I am very impressed with the passion of the faculty in R & D. Keep up the good work

Faizal E. Kottikollon and Shabana Faizal

Faizal Shabana Foundation, Bangalore
It is very good to see how committed you are with research

Dr. Claudio Almeida Quadros

Bahia State University, Brazil
An ideal facility positioning with cutting edge research and talented researchers right in the middle of a hospital, just what is needed for the translational research

Prof. Pauline Ford

School of Dentistry, The University of Queensland, Australia

Certifications