YRC YRC
Telephone

+91-824-2204668

Email Address

yrcoffice@yenepoya.edu.in
yrc.services@yenepoya.edu.in

Office Address

University Road, Deralakatte,
Mangalore 575018

YRC YRC

The Yenepoya Research Centre (YRC), established in 2008, is a constituent unit of Yenepoya (Deemed to be University). YRC is devoted to multidisciplinary research spanning fundamental, applied, and translational research. YRC has state-of-the-art facilities and resources to foster cutting-edge research and innovation involving various stakeholders. The Centre adheres to the highest ethical standards, research integrity, follows Good Laboratory Practices, and holds ISO 17025:2017 compliance certification.The biomedical research at YRC is complemented with the Yenepoya Medical College Hospital with super-speciality departments and other constituent institutions, including those specialising in alternative medicine. The passionate research team with international experience under a collaborative and inclusive environment drives the achievements by adpating transformative emerging technologies. The academic programs offered by YRC lays a robust foundation for a promising R&D career in academia and industry, as evidenced by the global alumni presence. YRC plays a pivotal role in promoting entrepreneurship among students and faculties through the Yenepoya Technology Incubator. The research thrust areas align with the nation’s effort in achieving the United Nations Sustainable Development Goals, while addressing the challenging issues at regional and national priority areas.

Vision

To generate new knowledge towards national development through quality research integrated with the highest ethical standards

Mission

  • To engage in high quality research integrating both basic and translational research across multiple disciplines, driving towards therapeutics of human health

  • To cultivate critical thinking that can spark creativity and innovation among students and young researchers to make them leaders in the field of science and technology

Divisions

Laboratory Services

Cancer Research and Therapeutics

Laboratory Services

Center for Systems Biology and Molecular Medicine

Laboratory Services

Division of Cell Biology and Molecular Genetics

Laboratory Services

Division of Data Analytics, Bioinformatics, and Structural Biology

Laboratory Services

Division of Microbiology and Biotechnology

Laboratory Services

Division of Neuroscience


Laboratory Services

Stem Cells and Regenerative Medicine Center

Laboratory Services

Smart Materials and Device

33

FACULTY

45

PhD Awarded

35

PATENTS

532

PUBLICATIONS

48

EXTRAMURAL GRANTS

News and Updates

MICON 2024 - Microbes for a Sustainable Future – A National Conference on 24th and 25th January 2024.

Workshop on Fundamentals and Techniques in Proteomics - Organized by CSBMM on May 29th & 31st May 2025.

Hands on Workshop on Metabolomic Analysis: Unlocking the Power of Mass Spectrometry - Organized by CSBMM on 26th & 28th May 2025.

Science Outreach Programme on 25th May 2025.

One Day Workshop on “Grant Writing for Early-Career Researchers: Breaking into Funding” - Organized by CSBMM on 23rd & 24th May 2025.

10th Annual State-level Conference of AMBKCCON 2025- Insight into Women’s Health - organized by CBMG division, in collaboration with the Biochemistry Department on 21st May 2025.

One Day Workshop on “Single Cell and Spatial Multiomics” - Organized by CSBMM on 12th March 2025.

International Women’s Day 2025 Celebration on 8th March 2025.

National Science Day celebration on 28th February 2025.

“Microglia and Neural Rhythms In Alzheimer's disease” – A Special Guest Lecture By Dr. Chinnakkaruppan Adaikkan on 20th February 2025.

The 4th National Conference MiCON 2025 on “Divergence and surveillance of microorganisms” on 25th January 2025.

Annual Day Celebration on 31st December 2024.

The snake Feeders: Ecology, Conservation and Snake Bite Solutions – A awarness session by Mr. Rithan Bopanna KG on 20 th November 2024.

Multi-omics and System Biology Approach Reveals Mitochondrial Associated Protiens In Alzheimer’s Diseases Progression – A Special Guest Lecture by Dr.Kaushik Kumar Dey on 16 th November 2024.

Mass spectrometry-based workshop on metabolomics and data analysis conducted from 26th to 28th September 2024.

Molecular Biology Techniques – A hands on training on 3rd to 6th September 2024.

Metabolomics – A workshop conducted from 3rd to 5th September 2024.

Cardiovascular Disease in India and the establishment of CSIR longitudinal cohort by Dr. Shanthanu Sengupta- A Guest Lecture on 4th September 2024.

Financial Planning: Get early, paving way to Vikasit Bharath- A guest talk by Ms. Sandhya .T. on 29th August 2024.

Basics of Data Analytics (Hybrid Mode) – A Workshop – 26th August to 6th September 2024.

Parkinson’s Disease: Our two lines to reconnoitre the Neurobiological Basis for Pathogenesis – A special Guest talk by Dr. Phalguni Anand Alladi on 24th August 2024.

Sadbhavana Diwas Celebration by NSS Unit – 20th August 2024

Aligning Grant Proposal with Sustainable Development Goals (SDG) for Viksit Bharat – A Symposium on 10th August 2024

Felicitation to Mr. Kushalappa Gowda for achieving a world record for a 25-hour yoga marathon on 2nd August 2024.

Computer - Aided Drug Design with BIOVIA Discovery Studio – Hands on Workshop – 1st to 2nd August 2024.

Understanding Office Ergonomics and Preventive Strategies in Musculosketal Disorders – A guest talk by Mr. Satyaraja. R. on 16th July 2024.

Navigating Intramural Funding Process and Application Requirements - A Workshop on 6th Jul 2024.

Biochemical and Biophysical Characterization of a Cancer drug target-Poly (ADP-ribose) polymerase 1 – A special guest lecture by Dr. Rajakumar Eerappa on 6th July 2024.

Mansoonia – Health Screening Camp and Awareness Program on 27th and June 28th 2024.

The Astrocyte Enigma: Unravelling the mystery of alpha synuclein pathology in Parkinson’s disease – A Special Guest Lecture by Dr. Aishwarya Raj on 20th June 2024.

Beating Burnout – A Guest Talk by Dr. Ravichandra Karkal on 19th June 2024

Global Warming – Awareness Program on 11th June 2024.

Enhancing Student Centred Teaching and Assessment – Short term Faculty Development Course on 27th to 29th April 2024.

Basic Biology and Clinical Application – Flow Cytometry workshop on 14th and 15th April 2024.

Drosophila Genetic Techniques – Hands on training on 28th to 30th March 2024.

National Science Day – 2024 celebration on 28th February 2024.

BUB1: A Multifaceted Kinase and its role in DNA Damage Signalling – A Special Lecture by Dr. Shyam Nyati on 19th February 2024.

Announcements

Call for PhD Admissions 2025-2026 Click

Achievements

Publications

  1. Prabhu A, Nidhi S, Shetty R, Shenoy PU, Das R. Identification of novel genetic variants associated with oral squamous cell carcinoma (OSCC) in South-West coast of India using targeted exome sequencing. Gene. 2025;933:148947.
  2. Banjan B, Raju R, Keshava Prasad TS, Abhinand CS. Computational identification of potential bioactive compounds from Triphala against alcoholic liver injury by targeting alcohol dehydrogenase. Molecular diversity. 2025;29(1):623-38.
  3. Saha S, Dutta G, Mohanto S, Prabhu A, Ghosh B, Pal S, Saha T, Ahmed MG. Sustainable synthesis of Cr2O3 nanoparticles utilizing Rauvolfia tetraphylla root extract for lung cancer treatment. Journal of Drug Delivery Science and Technology. 2025;104:106531.
  4. Kumara BN, Sonia J, Nazar H, Sarma RR, Venkadesh A, Prasad KS. Carboxymethyl hexanoyl chitosan drop-coated simple disposable paper electrochemical sensor for quality monitoring of vanillin. International Journal of Biological Macromolecules. 2025;291:138911.
  5. Ahmed SM, Laha S, Ifthikar MA, Das R, Das SP. MCM10: A potential biomarker for cervical cancer and precancerous lesions. Gene. 2025;936:149103.
  6. Nivedya T, Das R, Shanavas S, Rangaswamy B, Mukherjee C, Roy R, Sengupta J, Bose B, SK AK, Paira P. The role of ancillary ligands on benzodipyridophenazine-based Ru (ii)/Ir (iii) complexes in dark and light toxicity against TNBC cells. Dalton Transactions. 2025;54(12):4888-902.
  7. Das U, Shanavas S, Jayaprakash M, Senthil Kumar A, Kushwaha R, Mondal D, Maity S, Ghosh P, Kar B, Banerjee S, P SS. Reactive Oxygen Species Inducing Triazolylpyridine-Based Ru (II)/Ir (III) Complexes for Therapeutically Enhanced Triple-Negative Breast Cancer Treatment. Journal of Medicinal Chemistry. 2025;68(3):2764-78.
  8. Mahapatra BB, Das NK, Jadhav A, Roy A, Aravind NA. Global freshwater mollusc invasion: pathways, potential distribution, and niche shift. Hydrobiologia. 2025;852(5):1431-50.
  9. Suchithra KV, Hameed A, Surya S, Mahammad S, Arun AB. Dual phage-incorporated electrospun polyvinyl alcohol-eudragit nanofiber matrix for rapid healing of diabetic wound infected by Pseudomonas aeruginosa and Staphylococcus aureus. Drug Delivery and Translational Research. 2025;15(3):1092-108.
  10. Babu M, Rao RM, Babu A, Jerom JP, Gogoi A, Singh N, Seshadri M, Ray A, Shelley BP, Datta A. Antioxidant Effect of Naringin Demonstrated Through a Bayes’ Theorem Driven Multidisciplinary Approach Reveals its Prophylactic Potential as a Dietary Supplement for Ischemic Stroke. Molecular Neurobiology. 2025;62(3):3918-33.
  11. Venkatesan J, Murugan SS, Gupta PK, Anil S, Seong GH. Synthesis and Characterization of Gallic Acid Mediated Iridium Nanoparticles: Characterizations and Antioxidant Assessments. BioNanoScience. 2025;15(1):98.
  12. Singh SR, Kittur B, Bhavi SM, Thokchom B, Padti AC, Bhat SS, Bajire SK, Shastry RP, Srinath BS, Sillanpää M, Harini BP. The effect of Clitoria ternatea L. flowers-derived silver nanoparticles on A549 and L-132 human cell lines and their antibacterial efficacy in Caenorhabditis elegans in vivo. Hybrid Advances. 2025;8:100359.
  13. Balakrishnan B, Sarojini BK, Dayananda BS, Raghu SV, Venugopal DM, Prabhu A. Tamarind seed gum-based hydrogel for the targeted delivery of imidazobenzothiazole sulfonamide derivative as an anticancer agent. International Journal of Biological Macromolecules. 2025;295:139665.
  14. Sasikumar J, Shaikh HA, Naik B, Laha S, Das SP. Emergence of fungal hybrids–potential threat to humans. Microbial Pathogenesis. 2025:107278.
  15. Kumar P, Kudva A, Ramesh MR, Prabhu A, Anne G. Synthesis and characteristics of Fe/Ni/Cr oxide nanoparticles/PLA hybrid composite coatings on Mg–Zn–Ca alloy. Journal of Materials Research and Technology. 2025;35:2573-83.
  16. Rai A, Subramaniyan Y, Fathima F, Rekha PD. Broad-spectrum antimicrobial properties of linalool: supporting its pharmacological use in chronic wound infections by pathogens within the ESKAPE group and polymicrobial biofilms. World Journal of Microbiology and Biotechnology. 2025;41(3):99.
  17. Nisar M, Soman SP, Sreelan S, John L, Pinto SM, Kandasamy RK, Subbannayya Y, Prasad TS, Kanekar S, Raju R, Devasahayam Arokia Balaya R. ProteoArk: A One-Pot Proteomics Data Analysis and Visualization Tool for Biologists. Journal of proteome research. 2025;24(3):1008-16.
  18. Thomas MR, Badekila AK, Pai V, S N, Bhandary Y, Rai A, Kini S. Navigating tumor microenvironment barriers with nanotherapeutic strategies for targeting metastasis. Advanced Healthcare Materials. 2025;14(7):2403107.
  19. Avvadukkam J, Kodoth AK, Subramani TM, Bhandari SG, Kaiprath D, Kunhanna SB, Venugopal DM, Raghu SV. Development of pH?Responsive Hydrogel Excipient From Karaya Gum for Improved Oral Delivery of Donepezil Hydrochloride in Alzheimer's Disease Treatment. Journal of Applied Polymer Science. 2025;142(12):e56630.
  20. Mahin A, Gopalakrishnan AP, Ahmed M, Nisar M, John L, Shivamurthy PB, Ummar S, Varghese S, Modi PK, Pai VR, Prasad TS. Orchestrating intracellular calcium signaling Cascades by Phosphosite-Centric regulatory network: A comprehensive analysis on kinases CAMKK1 and CAMKK2. OMICS: A Journal of Integrative Biology. 2025;29(4):139-53.
  21. Biju P, Shenoy MM, Tellis R, Bhat R, Das R, Prabhu A, Ahmed MG, Ghate V. Novel Ketoconazole-Loaded Niosomal Gel with Carbamide for Enhanced Topical Delivery and Skin Hydration in Fungal Infections. Journal of Pharmaceutical Innovation. 2025;20(2):1-8.
  22. Sunitha MS, Naik P, Vishnumurthy KA, Adhikari AV. Synthesis of nonlinear heteroaromatic donor–acceptor conjugated polymers: Structural, theoretical, electrochemical, and optical properties. Polymer Engineering & Science. 2025;65(4):1752-64.
  23. Anjanayya G, Gani R, Hiremath M, Kavital A, Joshi S, Timanagouda K, Aziz RA, Raghu SV, Mathada AB. Exploration of a Novel Indole/Pyrazole Scaffold as a Promising Dual ?-Glucosidase and ?-Amylase Inhibitor: an In Vitro, In Vivo and In Silico Approach Toward Antidiabetic Drug Design. Russian Journal of Bioorganic Chemistry. 2025;51(2):755-71.
  24. Thiruvasagam S, Nihad M, Nayak S, Chaudhury D, Jose M, Shenoy PS. Comparative analysis of periodontal ligament stem cell characteristics in type 2 diabetic and non-diabetic patients with periodontitis. Journal of Oral and Maxillofacial Pathology. 2025;29(2):260-8.
  25. Banjan B, Vishwakarma R, Ramakrishnan K, Dev RR, Kalath H, Kumar P, Soman S, Raju R, Revikumar A, Rehman N, Abhinand CS. Targeting AFP-RAR? complex formation: a potential strategy for treating AFP-positive hepatocellular carcinoma. Molecular Diversity. 2025;29(2):1337-52.
  26. Shreevani K, Narayana B, Sarojini BK, Dayananda BS, Ganesha A, Rekha PD, Aziz RA, Raghu SV. Sustained release studies on 3-hydroxyflavone-loaded eudragit nanofibers to combat inflammatory conditions. Journal of Drug Delivery Science and Technology. 2025;106:106677.
  27. Shrivathsa VS, De S, Shetty S, Deekshitha K, Yuvaraj AR, Jayarama A, Prabhu S, Pinto R. Mechanistic insights into the formation of phase pure V2O5 2D nanostructures: Advanced fourier transform-raman spectroscopy analysis. Thin Solid Films. 2025;815:140642.
  28. Shrivastava S, Ratnacaram CK. Targeting the TGF-?-p21 axis: a critical regulator of bleomycin–induced cell cycle arrest and apoptosis in vitro-implication for progressive cervical cancer therapy. Medical Oncology. 2025;42(4):1-2.
  29. Keremane KS, Abdellah IM, Eletmany MR, Naik P, Anees P, Adhikari AV. Push–pull carbazole twin dyads as efficient sensitizers/co-sensitizers for DSSC application: effect of various anchoring groups on photovoltaic performance. Journal of Materials Chemistry C. 2025;13(18):9258-75.
  30. Konale M, Panakaje N, Parvin SR, Kulal A, Kambali U. Exploring the fusion of virtual fitting rooms and social media: a study on consumer behaviour and purchase intentions. Journal of Fashion Marketing and Management: An International Journal. 2025 Apr 9;29(4):728-57.
  31. Moharana SS, Mallick S, Pinto JR, Shenoy P S, Bose B. Osteo-inductive potential of homoeopathy potencies of Asafoetida on multipotent mesenchymal stem cells in vitro. 3 Biotech. 2025 May;15(5):124.
  32. Rao RS, Pinto L, Shastry RP, Dakal TC, Suravajhala P, Sashindran VK, Ghate SD. Azole resistance: patterns of amino acid substitutions in Candida sterol 14?-demethylase. Antonie van Leeuwenhoek. 2025 May;118(5):68.
  33. Varughese A, Balnadupete A, Ramesh P, Prasad TS, Nidha AB, Bhandary Y. Guardians turned culprits: NETosis and its influence on pulmonary fibrosis development. Molecular Biotechnology. 2025 May;67(5):1752-64.
  34. Ortiz A, Sansinenea E, Keswani C, Minkina T, Singh SP, Rekadwad B, Borriss R, Hefferon K, Hoat TX, Mitra D, Das Mohapatra PK. Bioengineering Bacillus spp. for sustainable crop production: Recent advances and resources for biotechnological applications. Journal of Plant Growth Regulation. 2025 May;44(5):1868-85.
  35. Spandana KJ, Rodrigues WJ, Ghate SD, Rao RS, Chandrashekar KR, Bhagya N. In Vitro Cytotoxic Potential and Integrated Network Pharmacology, Molecular Docking and Molecular Dynamic Approaches to Decipher the Mechanism of Gymnostachyum febrifugum Benth., in the Treatment of Breast Cancer. Applied Biochemistry and Biotechnology. 2025 May;197(5):2887-909.
  36. Mahmoud YA, Elkaliny NE, Darwish OA, Ashraf Y, Ebrahim RA, Das SP, Yahya G. Comprehensive review for aflatoxin detoxification with special attention to cold plasma treatment. Mycotoxin Research. 2025 May;41(2):277-300.
  37. Sriram S, Junaid PA, Sannegowda LK, Naveen MH, Prasad KS. Non-precious macrocycle embedded hybrid nanocomposites for efficient water oxidation. Sustainable Energy & Fuels. 2025;9(13):3646-58.
  38. Hanumanthappa R, Heggannavar GB, Banakar A, Achari DD, Ramesh Karoshi V, Krushna BR, Bepari A, Assad Assiri R, Nasser Altamimi H, Nanjaiah H, Sannaningaiah D. A Levodopa-Encapsulated Poly-?-Caprolactone Nanocomposite Improves the Motor Symptoms and Neurochemical Changes in a Rotenone-Induced Mouse Model of Parkinson’s Disease. ACS omega. 2025;10(19):19682-96.
  39. Jeena TM, Rakshitha C, Muneesa FM, Varughese A, Raju R, Krishnan D, Mugaranja K, Bhandary YP. miR-200 family: Gatekeepers of fibrinolytic regulation in lung pathologies during acute lung injury. Archives of Biochemistry and Biophysics. 2025;768:110398.
  40. Subramaniyan Y, Khan A, Mujeeburahiman M, Shivani M, Patil S, Lavanya N, Rekha PD. Urological metabolic conditions alter regulation of quorum-sensing system and virulence genes expression in uropathogenic Pseudomonas aeruginosa. Microbial Pathogenesis. 2025;203:107502.
  41. Ananthakrishnan AI, Mahin A, Prasad TS, Abhinand CS. Transcriptome Profiling and Viral? Human Interactome Insights Into HBV?Driven Oncogenic Alterations in Hepatocellular Carcinoma. Microbiology and Immunology. 2025.
  42. Shaji V, Amrutha S, Pervaje R, Abhinand CS, Raju R, Prasad TS, Modi PK. Exploration of Asparagus racemosus Willd for Alzheimer’s Disease Through Integrated Metabolomics and Network Pharmacology Analyses Targeting BACE1 Protein. Neurochemical Research. 2025;50(3):190.
  43. Hill MS, Minnis VR, Simpson AC, Salas Garcia MC, Bone D, Chung RK, Rushton E, Hameed A, Rekha PD, Gilbert JA, Venkateswaran K. Genomic description of Microbacterium mcarthurae sp. nov., a bacterium collected from the International Space Station that exhibits unique antimicrobial-resistant and virulent phenotype. mSystems. 2025;10(6):e00537-25.
  44. Khan DM, Rao VI, Moosabba MS, MubarakAli D, Manzoor M. Antimicrobial Resistance and Prevalence of ?-lactamase Genes Among Multidrug-Resistant Acinetobacter baumannii Isolates from Infected Diabetic Foot Ulcers. Bacteria. 2025;4(2):24.
  45. Narendradev ND, Ravindran R, Jain P, Chaudhary S, Velikkakath AK, Sudharman A, Janardhanan A, Nag TC, Yadav SC, Srinivasula SM. Endosomal RFFL ubiquitin ligase regulates mitochondrial morphology by targeting mitofusin 2. Journal of Cell Science. 2025;138(12):jcs263830.
  46. Nair SR, Nihad M, Shenoy PS, Gupta S, Bose B. Unveiling the effects of micro and nano plastics in embryonic development. Toxicology Reports. 2025:101954.
  47. Pinto JR, Deepika Bhat K, Bose B, Sudheer Shenoy P. Irisin: muscle’s novel player in endoplasmic reticulum stress and disease. Molecular and cellular biochemistry. 2025:1-5.
  48. Petukhova AA, Borisova NE, Dubinina TV, Sannegowda LK. Biomimicking thienyl-substituted cobalt phthalocyanine with carbon nanoparticles as hybrid electrocatalyst for augmenting oxygen reduction reaction. International Journal of Hydrogen Energy. 2025;135:285-94.
  49. Sheeraz AS, Kumara BN, Pereira P, Dsilva DJ, Mohanty PS, Prasad KS. Miniaturized 3D Printed Microfluidic Polymeric?Paper Hybrid Device for Colorimetric Detection of Arsenic (III). ChemistrySelect. 2025;10(22):e00277.
  50. Mallick S, Narayana VK, Rai AB, Upadhyay SS, Prasad TS, Shenoy S, Bose B. Hematopoietic stem cell conditioned media induces apoptosis in colorectal cancer stem cells via dysregulation of HSP90 and 26S proteasome system. The International Journal of Biochemistry & Cell Biology. 2025;184:106773.

Testimonials

An excellent facility with superior scope

Dr. VijayRaghavan

Secretary, DBT, New Delhi
Nice to see a bubbling group of researchers in a new upcoming research centre

Bharat Ratna Dr. C. N. R Rao

Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore
Proud to see such wonderful work at the facility and in faraway Mangalore

Dr. A. K. D’Cruz

Director-Tata Memorial Hospital, Mumbai
I was excited to see the advancement done by the institution in every aspect of medical science including latest laboratory in the premise. I pray the God that this institution will prosper and give benefit to the nation in health sector

Shri Shripad Yesso Naik

The Union Minister of AYUSH, Government of India
Wonderful facility! Research is the future to solve issues in medicine. I am very impressed with the passion of the faculty in R & D. Keep up the good work

Faizal E. Kottikollon and Shabana Faizal

Faizal Shabana Foundation, Bangalore
It is very good to see how committed you are with research

Dr. Claudio Almeida Quadros

Bahia State University, Brazil
An ideal facility positioning with cutting edge research and talented researchers right in the middle of a hospital, just what is needed for the translational research

Prof. Pauline Ford

School of Dentistry, The University of Queensland, Australia

Certifications