The Yenepoya Research Centre (YRC), established in 2008, is a constituent unit of Yenepoya (Deemed to be University). YRC is devoted to multidisciplinary research spanning fundamental, applied, and translational research. YRC has state-of-the-art facilities and resources to foster cutting-edge research and innovation involving various stakeholders. The Centre adheres to the highest ethical standards, research integrity, follows Good Laboratory Practices, and holds ISO 17025:2017 compliance certification.The biomedical research at YRC is complemented with the Yenepoya Medical College Hospital with super-speciality departments and other constituent institutions, including those specialising in alternative medicine. The passionate research team with international experience under a collaborative and inclusive environment drives the achievements by adpating transformative emerging technologies. The academic programs offered by YRC lays a robust foundation for a promising R&D career in academia and industry, as evidenced by the global alumni presence. YRC plays a pivotal role in promoting entrepreneurship among students and faculties through the Yenepoya Technology Incubator. The research thrust areas align with the nation’s effort in achieving the United Nations Sustainable Development Goals, while addressing the challenging issues at regional and national priority areas.

Vision

To generate new knowledge towards national development through quality research integrated with the highest ethical standards

Mission
  • To engage in high quality research integrating both basic and translational research across multiple disciplines, driving towards therapeutics of human health

  • To cultivate critical thinking that can spark creativity and innovation among students and young researchers to make them leaders in the field of science and technology

33

FACULTY

45

PhD Awarded

35

PATENTS

532

PUBLICATIONS

48

EXTRAMURAL GRANTS

News and Updates

MICON 2024 - Microbes for a Sustainable Future – A National Conference on 24th and 25th January 2024.

Workshop on Fundamentals and Techniques in Proteomics - Organized by CSBMM on May 29th & 31st May 2025.

Hands on Workshop on Metabolomic Analysis: Unlocking the Power of Mass Spectrometry - Organized by CSBMM on 26th & 28th May 2025.

Science Outreach Programme on 25th May 2025.

One Day Workshop on “Grant Writing for Early-Career Researchers: Breaking into Funding” - Organized by CSBMM on 23rd & 24th May 2025.

10th Annual State-level Conference of AMBKCCON 2025- Insight into Women’s Health - organized by CBMG division, in collaboration with the Biochemistry Department on 21st May 2025.

One Day Workshop on “Single Cell and Spatial Multiomics” - Organized by CSBMM on 12th March 2025.

International Women’s Day 2025 Celebration on 8th March 2025.

National Science Day celebration on 28th February 2025.

“Microglia and Neural Rhythms In Alzheimer's disease” – A Special Guest Lecture By Dr. Chinnakkaruppan Adaikkan on 20th February 2025.

The 4th National Conference MiCON 2025 on “Divergence and surveillance of microorganisms” on 25th January 2025.

Annual Day Celebration on 31st December 2024.

The snake Feeders: Ecology, Conservation and Snake Bite Solutions – A awarness session by Mr. Rithan Bopanna KG on 20 th November 2024.

Multi-omics and System Biology Approach Reveals Mitochondrial Associated Protiens In Alzheimer’s Diseases Progression – A Special Guest Lecture by Dr.Kaushik Kumar Dey on 16 th November 2024.

Mass spectrometry-based workshop on metabolomics and data analysis conducted from 26th to 28th September 2024.

Molecular Biology Techniques – A hands on training on 3rd to 6th September 2024.

Metabolomics – A workshop conducted from 3rd to 5th September 2024.

Cardiovascular Disease in India and the establishment of CSIR longitudinal cohort by Dr. Shanthanu Sengupta- A Guest Lecture on 4th September 2024.

Financial Planning: Get early, paving way to Vikasit Bharath- A guest talk by Ms. Sandhya .T. on 29th August 2024.

Basics of Data Analytics (Hybrid Mode) – A Workshop – 26th August to 6th September 2024.

Parkinson’s Disease: Our two lines to reconnoitre the Neurobiological Basis for Pathogenesis – A special Guest talk by Dr. Phalguni Anand Alladi on 24th August 2024.

Sadbhavana Diwas Celebration by NSS Unit – 20th August 2024

Aligning Grant Proposal with Sustainable Development Goals (SDG) for Viksit Bharat – A Symposium on 10th August 2024

Felicitation to Mr. Kushalappa Gowda for achieving a world record for a 25-hour yoga marathon on 2nd August 2024.

Computer - Aided Drug Design with BIOVIA Discovery Studio – Hands on Workshop – 1st to 2nd August 2024.

Understanding Office Ergonomics and Preventive Strategies in Musculosketal Disorders – A guest talk by Mr. Satyaraja. R. on 16th July 2024.

Navigating Intramural Funding Process and Application Requirements - A Workshop on 6th Jul 2024.

Biochemical and Biophysical Characterization of a Cancer drug target-Poly (ADP-ribose) polymerase 1 – A special guest lecture by Dr. Rajakumar Eerappa on 6th July 2024.

Mansoonia – Health Screening Camp and Awareness Program on 27th and June 28th 2024.

The Astrocyte Enigma: Unravelling the mystery of alpha synuclein pathology in Parkinson’s disease – A Special Guest Lecture by Dr. Aishwarya Raj on 20th June 2024.

Beating Burnout – A Guest Talk by Dr. Ravichandra Karkal on 19th June 2024

Global Warming – Awareness Program on 11th June 2024.

Enhancing Student Centred Teaching and Assessment – Short term Faculty Development Course on 27th to 29th April 2024.

Basic Biology and Clinical Application – Flow Cytometry workshop on 14th and 15th April 2024.

Drosophila Genetic Techniques – Hands on training on 28th to 30th March 2024.

National Science Day – 2024 celebration on 28th February 2024.

BUB1: A Multifaceted Kinase and its role in DNA Damage Signalling – A Special Lecture by Dr. Shyam Nyati on 19th February 2024.

Achievements

Publications

  1. Ingilela AB, Sekar P, Prabhu A, Balan AS. Investigating the Role of WEDM Surface Texturing in the Degradation and Biocompatibility of Mg-Zn-Ca alloy. International Journal of Lightweight Materials and Manufacture. 2025.
  2. Magham SV, Shanavas S, Pindiprolu SS, Nagappan K, More S, Chaudhury D, Ramakkamma AR, Singh MT, Wadhwani A, Bose B, Thaggikuppe Krishnamurthy P. Targeting GSK-3? to Modulate the Wnt Pathway: A Promising Neuroprotective Strategy for Alzheimer’s Disease. Molecular Pharmaceutics. 2025;22(11):6561-74.
  3. Shastry RP, Hameed A, Banerjee S, Prabhu A, Bajire SK, Pavan SR, Dhanyashree HR, Kotimoole CN, Stothard P, Surya S, Keshava Prasad TS. Tryptic oncopeptide secreted from the gut bacterium Cronobacter malonaticus PO3 promotes colorectal cancer. Scientific Reports. 2025;15(1):9958.
  4. Rai AB, Codi JA, Suchitha GP, Hemavathi KN, Dagamajalu S, Abhinand CS, Raju R, Prasad TS. Mapping growth differentiation factor-15 (GDF15)-mediated signaling pathways in cancer: insights into its role across different cancer types. Discover Oncology. 2025;16(1):1-5.
  5. Mahadevaswamy M, Suchitha GP, Pavan SR, Vivek HK, Nithya SD, Chandan S, Prasad SK, Keshava Prasad TS, Ahmad SF, Attia SM, Dagamajalu S. Naringin attenuates angiotensin II induced cardiac hypertrophy by inhibiting carbonic anhydrase II. Scientific Reports. 2025;15(1):11789.
  6. Poojary KK, Kunhiraman JP, Madhvacharya VV, Kumari S, Krishna N, S SP, K RG, Mutalik S, Ghani NK, Kabekkodu SP, Prasad TS. Bromodomain and extraterminal protein inhibitor JQ1 induces maturation arrest and disrupts the cytoplasmic organization in mouse oocytes under in vitro conditions. Scientific Reports. 2025;15(1):13448.
  7. Rawat A, Antil N, Meenakshi, Deshmukh B, Rai AB, Nagar A, Kumar N, Prasad TK, Karmodiya K, Sharma P. PfPPM2 signalling regulates asexual division and sexual conversion of human malaria parasite Plasmodium falciparum. Nature Communications. 2025;16(1):4790.
  8. Suhasini PC, Shetty VV, Bhat V, Shetty PK, Roopashree PG, Rao RM, Kumari NS. CD9 knockdown inhibits cell proliferation, migration, and invasion and augments apoptosis in tongue cancer cells through regulation of the EGFR signalling pathway. Molecular Biology Reports. 2025;52(1):525.
  9. Krishna S, Sequeira JJ, Mustak MS, Das R. Mitochondrial DNA HVRII (Poly-C) and HVRIII (Poly-CA) tandem repeat variation in the Koraga population. Egyptian Journal of Medical Human Genetics. 2025;26(1):106.
  10. Rahmath NA, Lin SY, Young CC, Hameed A. Volatile dimethyl disulphide emission from Burkholderia cepacia LS-044 suppresses metabolism and budding in caspofungin-resistant Nakaseomyces glabratus NT2. Scientific Reports. 2025;15(1):23307.
  11. Palollathil A, Dagamajalu S, Ahmed M, Vijayakumar M, Prasad TS, Raju R. The network map of mucin 1 mediated signaling in cancer progression and immune modulation. Discover Oncology. 2025;16(1):1404.
  12. Subramaniyan Y, Mujeeburahiman M, Khan A, Rekha PD. Overexpression of Agr quorum sensing system in uropathogenic Staphylococcus aureus in response to simulated urinary metabolic conditions enhancing growth and virulence. Medical Microbiology and Immunology. 2025;214(1):35.
  13. Mukherjee S, Das A, Karati D, Sinha D, Chakraborty M, Mishra PK, Ahmed MG. Design and Optimization of a Model Bcs Class II Drug-Loaded Glyceryl Monostearate Nanoparticles: Antidiabetic Efficacy and Teratogenic Safety in Zebrafish. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences. 2025;95(4):811-22.
  14. Siby CE, Beary I, Das R. Unravelling the genetic and epidemiological landscape of Handigodu syndrome in Southern India. Egyptian Journal of Medical Human Genetics. 2025;26(1):138.
  15. Baliga MS, Kalaimathi A, Jagadeesh NS, Ullal C, Rajeev AG, Krishna A, Simon P, George T, Palatty PL. Role of Nurses in Cancer Education, Screening, and Detection in the Community: Narrative Review Addressing the Existing Lacunae and Scope in India. Indian Journal of Medical and Paediatric Oncology. 2025.
  16. Naik P, Abdellah IM, Abdel?Shakour M, Keremane KS, Adhikari AV. Enhancing the Photoelectrochemical Performance of Ru (II)?Sensitized Dye?Sensitized Solar Cells Using Cyanopyridine?Based Cosensitizers. Energy Technology. 2025;13(12):2500294.
  17. GV YD, Pinto JR, Bose B, Shenoy S. Sulphated polysaccharides and biomaterials: Steering stem cell fate. Carbohydrate Polymers. 2025;369:124308.
  18. Hameed A, Young CC, Suchithra KV, Prabhu A, Dhanyashree HR, Shastry RP. Pantoea piersonii IIIF1SW-P2T triggers cytotoxicity through L-asparaginase-driven ammonium secretion and colonizes reproductive tract of Caenorhabditis elegans. Scientific Reports. 2025;15(1):35295.
  19. Karouia F, de Oliveira LC, Hameed A, Simpson A, Singh N, Rekha PD, Mason CE, Venkateswaran K. Genomic characterization of Microbacterium meiriae sp. nov., a novel bacterium isolated from the International Space Station. Scientific Reports. 2025;15(1):35770.
  20. Kumar P, Anne G, Ramesh S, Kudva SA, Ramesh MR, Doddamani M, Prabhu A, Sahu S. High-pressure torsion of biodegradable Mg? Zn? Mn alloy and investigate mechanical and corrosion behaviour. Scientific Reports. 2025;15(1):36168.
  21. Tejaswi L, Ramesh P, Aditya S, Raju R, Prasad TS. Computational neoantigen prediction for cancer immunotherapy. Genes & Immunity. 2025:1-8.
  22. Narayana S, Ahmed MG, Prabhu A, Paul K, Gowda BJ. Synthesis, Characterization, and In Vitro Evaluation of Anticancer Activity of Bevacizumab Encapsulated PLGA Nanoparticles on Ovarian Carcinoma Cells. Journal of Pharmaceutical Innovation. 2025;20(6):246.
  23. Mohanto S, Prabhu A, Nag S, Sultana R, Ahmed MG. Sustainable biogenic synthesis of cerium oxide nanoparticles (CeO2 NPs) using Cinnamomum verum bark: An in vitro physicochemical and biological assessment. Discover Materials. 2025;5(1):1-21.
  24. Kudva SA, Anne G, Kumar P, Prabhu A, Ramesh S. Development of biodegradable Mg-Zn-Zr-based temporary implant materials through multidirectional forging and laser shock peening. Scientific Reports. 2025;15(1):41613.
  25. Sonam A, Hameed A, Stothard P, Grant JR, Arun AB. Draft genome sequence of Leptospira sp. SA-E8, isolated from a farmland soil. Microbiology Resource Announcements. 2025;14(12):e00929-25.
  26. Megha SK, Subramaniyan Y, Baby BM, Lobo S, Mujeeburahiman M, Rekha PD. Influence of Nutritional Conditions on Coexistence of Pseudomonas aeruginosa and Staphylococcus aureus in the Dual?Species Biofilm. APMIS. 2025;133(12):e70123.
  27. Kalayakkattil S, Indu AA, Sunil P, Nekkanti H, Shet S, Das R. Temporal Profiling of SARS-CoV-2 Variants Using BioEnrichPy: A Network-Based Insight into Host Disruption and Neurodegeneration. COVID. 2025;5(12):203.
  28. Adyanthaya S, Prabhu A, Bhandary Y, Balnadupete A, Abdulla R. In vitro evaluation of cytoproliferative activity of areca nut varieties on murine fibroblasts. Journal of Oral and Maxillofacial Pathology. 2025;29(4):511-8.
  29. Prabhu VD, Hegde S, Abdulla R, Prabhu A, Prabhu RV, Akhila HS. Foeniculum vulgare as a Novel Therapeutic Agent in the Treatment of Oral Squamous Cell Carcinoma: An In vitro Cell Line Pilot Study. Journal of Indian Academy of Oral Medicine and Radiology. 2025;37(4):461-5.
  30. Suchithra KV, Hameed A, Rekha PD, Stothard P, Arun AB. A novel Kayvirus species phage RuSa1 removes biofilm and lyses multiple clinical strains of methicillin resistant Staphylococcus aureus. Scientific Reports. 2025;15(1):7358.
  31. Amrutha S, Abhinand CS, Upadhyay SS, Parvaje R, Prasad TS, Modi PK. Network pharmacology and metabolomics analysis of Tinospora cordifolia reveals BACE1 and MAOB as potential therapeutic targets for neuroprotection in Alzheimer’s disease. Scientific Reports. 2025;15(1):8103.
  32. Páll-Gergely B, Gojšina V, Aravind NA. A review of Chamalycaeus, Cycloryx and Dicharax species of the Himalaya and Myanmar and seven new species of Alycaeinae from the Blue Mountain, Mizoram, India (Gastropoda, Caenogastropoda, Cyclophoridae). European Journal of Taxonomy. 2025;1029:3131.
  33. Das R, Shanavas S, Das U, Kushwaha R, Chakrabarty R, Banerjee S, Chaudhury D, Shenoy P S, Bose B, Paira P. Turning the Spotlight Away from PDT: Chemodynamic Dominance of 2-(2-Bromopyridin-4-yl)-1 H-imidazo [4, 5-f][1, 10] phenanthroline Based Ru (II)/Ir (III)/Re (I) Complexes against MDA-MB-231. Journal of Medicinal Chemistry. 2025;68(24):26263-79.
  34. Krishnan S.; Kanthaje S.; Rekha P.D.; Mujeeburahiman M.; Ratnacaram C.K.. Expanding frontiers in liquid biopsy-discovery and validation of circulating biomarkers in renal cell carcinoma and bladder cancer. International Review of Cell and Molecular Biology. 2025; 391()
  35. Rai A.B.; Codi J.A.K.; Kotimoole C.N.; Ramesh P.; Narayana V.K.; Shaji V.; Prasad T.S.K.. Data-Independent Acquisition Analysis to Identify Serum Biomarkers and Neoantigens for Differentiating Colorectal Cancer from Inflammatory Bowel Diseases. Journal of Proteome Research. 2025; ()
  36. Hameed A.; McDonagh F.; Sengupta P.; Miliotis G.; Sivabalan S.K.M.; Szydlowski L.; Simpson A.; Singh N.K.; Rekha P.D.; Raman K.; Venkateswaran K.. Neobacillus driksii sp. nov. isolated from a Mars 2020 spacecraft assembly facility and genomic potential for lasso peptide production in Neobacillus. Microbiology Spectrum . 2025; 13(1)
  37. Nekrakalaya B.; Kotimoole C.N.; Arefian M.; Prasad T.S.K.; Palliyath G.K.; Veerappa Hanumanthappa P.; Pandian Ramasubramania T.P.; Bangalore Jayaseelan N.K.; Muddumadiah C.; Santhappan P.; Muliyar Krishna R.. A Gel-Free Genome Annotation Provides Insights into the Proteome of the Oomycete Phytophthora meadii, a Disease-Causing Pathogen in Economically Important Crops. OMICS A Journal of Integrative Biology. 2025; ()
  38. Pavan S.R.; Prabhu A.. Black Phosphorus for Biosensing and Imaging Applications. Two-Dimensional Nanomaterials for Biosensing and Imaging Applications. 2025; ()
  39. Salam A.S.A.; Anchan R.V.; Murugan S.S.; Majhi D.; Venkatesan J.. The Potential Use of Algae-Derived Green Nanomaterials in Cancer Therapy. Nano-formulation of Dietary Phytochemicals for Cancer Management. 2025; ()
  40. Manzoor M.; Suryavanshi M.V.; Mujeeburahiman M.; Arun A.B.; Miller A.W.; Shouche Y.S.; Rekha P.D.. Urine microbiome profiles in patients with different types of kidney stones. FEMS Microbiology Letters. 2025; 372()
  41. Prashanth S.; Kadandelu M.; Raghu S.V.; Prasad K.S.; Adhikari A.V.. Conductive nano nickel oxide/hydroxide paper electrochemical sensor for serotonin detection in genetically engineered Drosophila. Journal of Materials Chemistry B. 2025; ()
  42. Dcunha R.; Aravind A.; Bhaskar S.; Mutalik S.; Mutalik S.; Kalthur S.G.; Kumar A.; Hegde P.; Adiga S.K.; Zhao Y.; Kannan N.; Prasad T.S.K.; Kalthur G.. Enhanced cell survival in prepubertal testicular tissue cryopreserved with membrane lipids and antioxidants rich cryopreservation medium. Cell and Tissue Research. 2025; 399(1)
  43. Kapoor A.; Meitei N.S.; Bisht V.S.; Najar M.A.; Giri K.; Prasad T.S.K.; Ambatipudi K.. Lactation stage-specific variations in health and lipid-associated milk fat globule membrane proteins in Holstein Friesian cow and Murrah buffalo. International Dairy Journal. 2025; 160()
  44. Bhat S.; Narayana V.K.; Prasad T.S.K.. Metabolomics studies in cushing’s syndrome: recent developments and perspectives. Expert Review of Proteomics. 2025; 22(2)
  45. Ramesh P.; Kandel Codi J.A.; Prasad T.S.K.. Proteins Biomarkers for Diagnosing Gastric Cancers: Perspectives Through Mass Spectrometry-Based Discoveries. Protein Biomarkers: Discovery and Applications in Clinical Diagnostics. 2025; ()
  46. Yukta; Sarkar O.; Mutthuraj D.; Dagamajalu S.; Basalingappa K.M.. Small Molecule Therapeutics in Breast Cancer: Current Approaches and Future Directions. Small Molecules for Cancer Treatment. 2025; ()
  47. Parate S.S.; Viayakumar M.; Prasad T.S.K.. Ex Vivo Drug Assay as a Potential Hospital-Based Testing Platform for Clinical Research and Personalized Treatment for Solid Tumors. Protein Biomarkers: Discovery and Applications in Clinical Diagnostics. 2025; ()
  48. Upadhyay S.; Shetty R.; Prasad T.S.K.. Prospects for the Discovery of Actionable Molecular Targets for Triple Negative Breast Cancer. Protein Biomarkers: Discovery and Applications in Clinical Diagnostics. 2025; ()
  49. Aravind A.; Shaji V.; Ahmed M.; Dagamajalu S.; Vijayakumar M.; Prasad T.S.K.; Raju R.. An assembled molecular signaling map of interleukin-24: a resource to decipher its multifunctional immunoregulatory role in pathophysiological conditions. Frontiers in Immunology. 2025; 16()
  50. Gopalakrishnan A.P.; Shivamurthy P.B.; Ahmed M.; Ummar S.; Ramesh P.; Thomas S.D.; Mahin A.; Nisar M.; Soman S.; Subbannayya Y.; Raju R.. Positional distribution and conservation of major phosphorylated sites in the human kinome. Frontiers in Molecular Biosciences. 2025; 12()

Testimonials

An excellent facility with superior scope

Dr. VijayRaghavan

Secretary, DBT, New Delhi
Nice to see a bubbling group of researchers in a new upcoming research centre

Bharat Ratna Dr. C. N. R Rao

Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore
Proud to see such wonderful work at the facility and in faraway Mangalore

Dr. A. K. D’Cruz

Director-Tata Memorial Hospital, Mumbai
I was excited to see the advancement done by the institution in every aspect of medical science including latest laboratory in the premise. I pray the God that this institution will prosper and give benefit to the nation in health sector

Shri Shripad Yesso Naik

The Union Minister of AYUSH, Government of India
Wonderful facility! Research is the future to solve issues in medicine. I am very impressed with the passion of the faculty in R & D. Keep up the good work

Faizal E. Kottikollon and Shabana Faizal

Faizal Shabana Foundation, Bangalore
It is very good to see how committed you are with research

Dr. Claudio Almeida Quadros

Bahia State University, Brazil
An ideal facility positioning with cutting edge research and talented researchers right in the middle of a hospital, just what is needed for the translational research

Prof. Pauline Ford

School of Dentistry, The University of Queensland, Australia

Certifications